What Antibiotics Effectively Treat Corneal Ulcer?

Determining the most effective treatment for a corneal ulcer depends on identifying the specific underlying cause. When the precise cause of the ulcer remains uncertain, doctors typically initiate treatment with broad-spectrum antibiotic eye drops, which are effective against a wide range of bacteria. However, once the cause is definitively diagnosed, a more tailored approach can be pursued. Treatment options may include specialized eye drops designed to combat bacteria, herpes, other viruses, or fungal infections, depending on the culprit. In cases of severe ulcers that do not respond to conventional treatments, a corneal transplant might be necessary to restore vision and preserve eye health.

The primary course of action for treating bacterial corneal ulcers involves initiating therapy with a broad-spectrum antibiotic. This approach is recommended, particularly when the specific bacterial strain causing the ulcer is unknown. This is because the majority of corneal ulcers encountered in clinical practice are typically of bacterial origin. Dr. Colby, a renowned expert in the field, emphasizes that broad-spectrum fluoroquinolone antibiotics are a suitable initial choice for treatment. These antibiotics often yield positive results, even if the infecting bacteria are not specifically susceptible to them. Dr. Colby’s insights, shared on October 6, 2020, highlight the importance of this approach in managing bacterial corneal ulcers effectively.